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The host cell secretory pathway mediates the export of Leishmania virulence factors out of the parasitophorous vacuole

To colonize phagocytes, Leishmania subverts microbicidal processes through components of its surface coat that include lipophosphoglycan and the GP63 metalloprotease. How these virulence glycoconjugates are shed, exit the parasitophorous vacuole (PV), and traffic within host cells is poorly understo...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Arango Duque, Guillermo, Jardim, Armando, Gagnon, Étienne, Fukuda, Mitsunori, Descoteaux, Albert
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6687203/
https://ncbi.nlm.nih.gov/pubmed/31356625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007982
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