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The host cell secretory pathway mediates the export of Leishmania virulence factors out of the parasitophorous vacuole

To colonize phagocytes, Leishmania subverts microbicidal processes through components of its surface coat that include lipophosphoglycan and the GP63 metalloprotease. How these virulence glycoconjugates are shed, exit the parasitophorous vacuole (PV), and traffic within host cells is poorly understo...

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Vydáno v:PLoS Pathog
Hlavní autoři: Arango Duque, Guillermo, Jardim, Armando, Gagnon, Étienne, Fukuda, Mitsunori, Descoteaux, Albert
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6687203/
https://ncbi.nlm.nih.gov/pubmed/31356625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007982
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