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The host cell secretory pathway mediates the export of Leishmania virulence factors out of the parasitophorous vacuole

To colonize phagocytes, Leishmania subverts microbicidal processes through components of its surface coat that include lipophosphoglycan and the GP63 metalloprotease. How these virulence glycoconjugates are shed, exit the parasitophorous vacuole (PV), and traffic within host cells is poorly understo...

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Detalles Bibliográficos
Publicado en:PLoS Pathog
Main Authors: Arango Duque, Guillermo, Jardim, Armando, Gagnon, Étienne, Fukuda, Mitsunori, Descoteaux, Albert
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6687203/
https://ncbi.nlm.nih.gov/pubmed/31356625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007982
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