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Insulin Receptor Substrate-1 (IRS-1) and IRS-2 expression levels are associated with prognosis in non-small cell lung cancer (NSCLC)

The insulin-like growth factor-1 (IGF-1) signaling pathway has been implicated in non-small cell lung cancer (NSCLC) outcomes and resistance to targeted therapies. However, little is known regarding the molecular mechanisms by which this pathway contributes to the biology of NSCLC. The insulin recep...

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Udgivet i:PLoS One
Main Authors: Piper, Andrew J., Clark, Jennifer L., Mercado-Matos, Jose, Matthew-Onabanjo, Asia N., Hsieh, Chung-Cheng, Akalin, Ali, Shaw, Leslie M.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6687170/
https://ncbi.nlm.nih.gov/pubmed/31393907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0220567
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