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Insulin Receptor Substrate-1 (IRS-1) and IRS-2 expression levels are associated with prognosis in non-small cell lung cancer (NSCLC)

The insulin-like growth factor-1 (IGF-1) signaling pathway has been implicated in non-small cell lung cancer (NSCLC) outcomes and resistance to targeted therapies. However, little is known regarding the molecular mechanisms by which this pathway contributes to the biology of NSCLC. The insulin recep...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Piper, Andrew J., Clark, Jennifer L., Mercado-Matos, Jose, Matthew-Onabanjo, Asia N., Hsieh, Chung-Cheng, Akalin, Ali, Shaw, Leslie M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6687170/
https://ncbi.nlm.nih.gov/pubmed/31393907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0220567
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