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A More Efficient Conditional Mouse Model of Dravet Syndrome: Implications for Epigenetic Selection and Sex-Dependent Behaviors
BACKGROUND: Dravet Syndrome (DS) is an epileptic disorder characterized by spontaneous and thermally-induced seizures, hyperactivity, cognitive deficits, autistic-like behaviors, and Sudden Unexpected Death in Epilepsy (SUDEP). DS is caused by de novo loss-of-function mutations in the SCN1A gene. Se...
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| Publicado en: | J Neurosci Methods |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6686874/ https://ncbi.nlm.nih.gov/pubmed/31265868 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneumeth.2019.108315 |
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