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HDACs control RUNX2 expression in cancer cells through redundant and cell context-dependent mechanisms
BACKGROUND: RUNX2 is a Runt-related transcription factor required during embryogenesis for skeletal development and morphogenesis of other organs including thyroid and breast gland. Consistent evidence indicates that RUNX2 expression is aberrantly reactivated in cancer and supports tumor progression...
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| Publicado no: | J Exp Clin Cancer Res |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6686443/ https://ncbi.nlm.nih.gov/pubmed/31395086 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1350-5 |
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