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HDACs control RUNX2 expression in cancer cells through redundant and cell context-dependent mechanisms

BACKGROUND: RUNX2 is a Runt-related transcription factor required during embryogenesis for skeletal development and morphogenesis of other organs including thyroid and breast gland. Consistent evidence indicates that RUNX2 expression is aberrantly reactivated in cancer and supports tumor progression...

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Detalles Bibliográficos
Publicado en:J Exp Clin Cancer Res
Autores principales: Manzotti, Gloria, Torricelli, Federica, Donati, Benedetta, Sancisi, Valentina, Gugnoni, Mila, Ciarrocchi, Alessia
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6686443/
https://ncbi.nlm.nih.gov/pubmed/31395086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1350-5
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