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HDACs control RUNX2 expression in cancer cells through redundant and cell context-dependent mechanisms
BACKGROUND: RUNX2 is a Runt-related transcription factor required during embryogenesis for skeletal development and morphogenesis of other organs including thyroid and breast gland. Consistent evidence indicates that RUNX2 expression is aberrantly reactivated in cancer and supports tumor progression...
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| Опубликовано в: : | J Exp Clin Cancer Res |
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| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BioMed Central
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6686443/ https://ncbi.nlm.nih.gov/pubmed/31395086 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1350-5 |
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