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HDACs control RUNX2 expression in cancer cells through redundant and cell context-dependent mechanisms

BACKGROUND: RUNX2 is a Runt-related transcription factor required during embryogenesis for skeletal development and morphogenesis of other organs including thyroid and breast gland. Consistent evidence indicates that RUNX2 expression is aberrantly reactivated in cancer and supports tumor progression...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Exp Clin Cancer Res
Prif Awduron: Manzotti, Gloria, Torricelli, Federica, Donati, Benedetta, Sancisi, Valentina, Gugnoni, Mila, Ciarrocchi, Alessia
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6686443/
https://ncbi.nlm.nih.gov/pubmed/31395086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1350-5
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