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HDACs control RUNX2 expression in cancer cells through redundant and cell context-dependent mechanisms

BACKGROUND: RUNX2 is a Runt-related transcription factor required during embryogenesis for skeletal development and morphogenesis of other organs including thyroid and breast gland. Consistent evidence indicates that RUNX2 expression is aberrantly reactivated in cancer and supports tumor progression...

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Библиографические подробности
Опубликовано в: :J Exp Clin Cancer Res
Главные авторы: Manzotti, Gloria, Torricelli, Federica, Donati, Benedetta, Sancisi, Valentina, Gugnoni, Mila, Ciarrocchi, Alessia
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2019
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6686443/
https://ncbi.nlm.nih.gov/pubmed/31395086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1350-5
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