Paxillin S273 Phosphorylation Regulates Adhesion Dynamics and Cell Migration through a Common Protein Complex with PAK1 and βPIX

Cell migration is an important biological phenomenon involved in many homeostatic and aberrant physiological processes. Phosphorylation of the focal adhesion adaptor protein, paxillin, on serine 273 (S273) has been implicated as a key regulator of cell migration. Here, it is shown that phosphorylati...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Rajah, Abira, Boudreau, Colton G., Ilie, Alina, Wee, Tse-Luen, Tang, Kaixi, Borisov, Aleksandar Z., Orlowski, John, Brown, Claire M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2019
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6686007/
https://ncbi.nlm.nih.gov/pubmed/31391572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-47722-3
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