Paxillin S273 Phosphorylation Regulates Adhesion Dynamics and Cell Migration through a Common Protein Complex with PAK1 and βPIX

Cell migration is an important biological phenomenon involved in many homeostatic and aberrant physiological processes. Phosphorylation of the focal adhesion adaptor protein, paxillin, on serine 273 (S273) has been implicated as a key regulator of cell migration. Here, it is shown that phosphorylati...

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Published in:Sci Rep
Main Authors: Rajah, Abira, Boudreau, Colton G., Ilie, Alina, Wee, Tse-Luen, Tang, Kaixi, Borisov, Aleksandar Z., Orlowski, John, Brown, Claire M.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6686007/
https://ncbi.nlm.nih.gov/pubmed/31391572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-47722-3
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