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Phosphorylation of tyrosine 285 of PAK1 facilitates βPIX/GIT1 binding and adhesion turnover

The p21-activated serine-threonine kinase (PAK1) regulates cell motility and adhesion. We have previously shown that the prolactin (PRL)-activated tyrosine kinase JAK2 phosphorylates PAK1 in vivo and in vitro and identified tyrosines 153, 201, and 285 in PAK1 as sites of JAK2 tyrosyl phosphorylation...

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Detalles Bibliográficos
Publicado en:FASEB J
Main Authors: Hammer, Alan, Oladimeji, Peter, De Las Casas, Luis E., Diakonova, Maria
Formato: Artigo
Idioma:Inglês
Publicado: Federation of American Societies for Experimental Biology 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4422366/
https://ncbi.nlm.nih.gov/pubmed/25466889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.14-259366
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