Tyrosyl Phosphorylated PAK1 Regulates Breast Cancer Cell Motility in Response to Prolactin through Filamin A

The p21-activated serine-threonine kinase (PAK1) is activated by small GTPase-dependent and -independent mechanisms and regulates cell motility. Both PAK1 and the hormone prolactin (PRL) have been implicated in breast cancer by numerous studies. We have previously shown that the PRL-activated tyrosi...

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Main Authors: Hammer, Alan, Rider, Leah, Oladimeji, Peter, Cook, Leslie, Li, Quanwen, Mattingly, Raymond R., Diakonova, Maria
Formato: Artigo
Idioma:Inglês
Publicado: Endocrine Society 2013
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Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3589676/
https://ncbi.nlm.nih.gov/pubmed/23340249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2012-1291
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