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PAK1 Regulates Breast Cancer Cell Invasion through Secretion of Matrix Metalloproteinases in Response to Prolactin and Three-Dimensional Collagen IV

p21-Activated serine-threonine kinase (PAK1) is implicated in breast cancer. We have shown previously that PAK1 is tyrosyl phosphorylated by prolactin (PRL)-activated Janus tyrosine kinase (JAK2). Although a role for both PRL and PAK1 in breast cancer is widely acknowledged, the mechanism remains po...

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Bibliografische gegevens
Hoofdauteurs: Rider, Leah, Oladimeji, Peter, Diakonova, Maria
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Endocrine Society 2013
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3706840/
https://ncbi.nlm.nih.gov/pubmed/23744893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2012-1322
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