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Intracellular Ca(2+) Homeostasis and Nuclear Export Mediate Exit from Naive Pluripotency
Progression through states of pluripotency is required for cells in early mammalian embryos to transition away from heightened self-renewal and toward competency for lineage specification. Here, we use a CRISPR mutagenesis screen in mouse embryonic stem cells (ESCs) to identify unexpected roles for...
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| Udgivet i: | Cell Stem Cell |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6685429/ https://ncbi.nlm.nih.gov/pubmed/31104942 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2019.04.015 |
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