Loading...

KLF4 Nuclear Export Requires ERK Activation and Initiates Exit from Naive Pluripotency

Cooperative action of a transcription factor complex containing OCT4, SOX2, NANOG, and KLF4 maintains the naive pluripotent state; however, less is known about the mechanisms that disrupt this complex, initiating exit from pluripotency. We show that, as embryonic stem cells (ESCs) exit pluripotency,...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Stem Cell Reports
Main Authors: Dhaliwal, Navroop K., Miri, Kamelia, Davidson, Scott, Tamim El Jarkass, Hala, Mitchell, Jennifer A.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6000723/
https://ncbi.nlm.nih.gov/pubmed/29526737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2018.02.007
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!