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KLF4 protein stability regulated by interaction with pluripotency transcription factors overrides transcriptional control

Embryonic stem (ES) cells are regulated by a network of transcription factors that maintain the pluripotent state. Differentiation relies on down-regulation of pluripotency transcription factors disrupting this network. While investigating transcriptional regulation of the pluripotency transcription...

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Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Dhaliwal, Navroop K., Abatti, Luis E., Mitchell, Jennifer A.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6672055/
https://ncbi.nlm.nih.gov/pubmed/31221664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.324319.119
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