A dynamic interplay of enhancer elements regulates Klf4 expression in naïve pluripotency

Transcription factor (TF)-directed enhanceosome assembly constitutes a fundamental regulatory mechanism driving spatiotemporal gene expression programs during animal development. Despite decades of study, we know little about the dynamics or order of events animating TF assembly at cis-regulatory el...

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Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Xie, Liangqi, Torigoe, Sharon E., Xiao, Jifang, Mai, Daniel H., Li, Li, Davis, Fred P., Dong, Peng, Marie-Nelly, Herve, Grimm, Jonathan, Lavis, Luke, Darzacq, Xavier, Cattoglio, Claudia, Liu, Zhe, Tjian, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5666677/
https://ncbi.nlm.nih.gov/pubmed/28982762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.303321.117
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