Caricamento...
KLF4 Nuclear Export Requires ERK Activation and Initiates Exit from Naive Pluripotency
Cooperative action of a transcription factor complex containing OCT4, SOX2, NANOG, and KLF4 maintains the naive pluripotent state; however, less is known about the mechanisms that disrupt this complex, initiating exit from pluripotency. We show that, as embryonic stem cells (ESCs) exit pluripotency,...
Salvato in:
| Pubblicato in: | Stem Cell Reports |
|---|---|
| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Elsevier
2018
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6000723/ https://ncbi.nlm.nih.gov/pubmed/29526737 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2018.02.007 |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|