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Tofacitinib facilitates the expansion of myeloid-derived suppressor cells and ameliorates interstitial lung disease in SKG mice

BACKGROUND: Rheumatoid arthritis-associated interstitial lung disease (RA-ILD) is a sometimes life-threatening complication in RA patients. SKG mice develop not only arthritis but also an ILD resembling RA-ILD. We previously reported that tofacitinib, a JAK inhibitor, facilitates the expansion of my...

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Detalhes bibliográficos
Publicado no:Arthritis Res Ther
Main Authors: Sendo, Sho, Saegusa, Jun, Yamada, Hirotaka, Nishimura, Keisuke, Morinobu, Akio
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6685227/
https://ncbi.nlm.nih.gov/pubmed/31387650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-019-1963-2
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