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Additive effects of inhibiting both mTOR and glutamine metabolism on the arthritis in SKG mice

Glutamine metabolism and the mechanistic target of rapamycin (mTOR) pathway are activated cooperatively in the differentiation and activation of inflammatory immune cells. But the combined inhibition of both pathways was rarely investigated. This study investigated how inhibiting both glutamine meta...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Ueda, Yo, Saegusa, Jun, Okano, Takaichi, Sendo, Sho, Yamada, Hirotaka, Nishimura, Keisuke, Morinobu, Akio
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6476881/
https://ncbi.nlm.nih.gov/pubmed/31011190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-42932-1
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