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Additive effects of inhibiting both mTOR and glutamine metabolism on the arthritis in SKG mice

Glutamine metabolism and the mechanistic target of rapamycin (mTOR) pathway are activated cooperatively in the differentiation and activation of inflammatory immune cells. But the combined inhibition of both pathways was rarely investigated. This study investigated how inhibiting both glutamine meta...

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書目詳細資料
發表在:Sci Rep
Main Authors: Ueda, Yo, Saegusa, Jun, Okano, Takaichi, Sendo, Sho, Yamada, Hirotaka, Nishimura, Keisuke, Morinobu, Akio
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2019
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6476881/
https://ncbi.nlm.nih.gov/pubmed/31011190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-42932-1
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