Soluble guanylate cyclase stimulator reduced the gastrointestinal fibrosis in bleomycin-induced mouse model of systemic sclerosis

BACKGROUND: Systemic sclerosis (SSc) is a chronic autoimmune-mediated connective tissue disorder. Although the etiology of the disease remains undetermined, SSc is characterized by fibrosis and proliferative vascular lesions of the skin and internal organs. SSc involves the gastrointestinal tract in...

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Vydáno v:Arthritis Res Ther
Hlavní autoři: Yamamoto, Yuzuru, Okano, Takaichi, Yamada, Hirotaka, Akashi, Kengo, Sendo, Sho, Ueda, Yo, Morinobu, Akio, Saegusa, Jun
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2021
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8091711/
https://ncbi.nlm.nih.gov/pubmed/33941248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-021-02513-y
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