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Soluble guanylate cyclase stimulator reduced the gastrointestinal fibrosis in bleomycin-induced mouse model of systemic sclerosis

BACKGROUND: Systemic sclerosis (SSc) is a chronic autoimmune-mediated connective tissue disorder. Although the etiology of the disease remains undetermined, SSc is characterized by fibrosis and proliferative vascular lesions of the skin and internal organs. SSc involves the gastrointestinal tract in...

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Detalhes bibliográficos
Publicado no:Arthritis Res Ther
Main Authors: Yamamoto, Yuzuru, Okano, Takaichi, Yamada, Hirotaka, Akashi, Kengo, Sendo, Sho, Ueda, Yo, Morinobu, Akio, Saegusa, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8091711/
https://ncbi.nlm.nih.gov/pubmed/33941248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-021-02513-y
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