Soluble guanylate cyclase stimulator reduced the gastrointestinal fibrosis in bleomycin-induced mouse model of systemic sclerosis

BACKGROUND: Systemic sclerosis (SSc) is a chronic autoimmune-mediated connective tissue disorder. Although the etiology of the disease remains undetermined, SSc is characterized by fibrosis and proliferative vascular lesions of the skin and internal organs. SSc involves the gastrointestinal tract in...

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Bibliographic Details
Published in:Arthritis Res Ther
Main Authors: Yamamoto, Yuzuru, Okano, Takaichi, Yamada, Hirotaka, Akashi, Kengo, Sendo, Sho, Ueda, Yo, Morinobu, Akio, Saegusa, Jun
Format: Artigo
Language:Inglês
Published: BioMed Central 2021
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8091711/
https://ncbi.nlm.nih.gov/pubmed/33941248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-021-02513-y
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