Soluble guanylate cyclase stimulator reduced the gastrointestinal fibrosis in bleomycin-induced mouse model of systemic sclerosis

BACKGROUND: Systemic sclerosis (SSc) is a chronic autoimmune-mediated connective tissue disorder. Although the etiology of the disease remains undetermined, SSc is characterized by fibrosis and proliferative vascular lesions of the skin and internal organs. SSc involves the gastrointestinal tract in...

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Pubblicato in:Arthritis Res Ther
Autori principali: Yamamoto, Yuzuru, Okano, Takaichi, Yamada, Hirotaka, Akashi, Kengo, Sendo, Sho, Ueda, Yo, Morinobu, Akio, Saegusa, Jun
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2021
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8091711/
https://ncbi.nlm.nih.gov/pubmed/33941248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-021-02513-y
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