Histone deacetylase inhibition alters dendritic cells to assume a tolerogenic phenotype and ameliorates arthritis in SKG mice

INTRODUCTION: The purpose of this study was to elucidate the effects of histone deacetylase inhibition on the phenotype and function of dendritic cells and on arthritis in SKG mice. METHODS: Arthritis was induced in SKG mice by zymosan A injection. Trichostatin A, a histone deacetylase inhibitor, wa...

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Detalhes bibliográficos
Main Authors: Misaki, Kenta, Morinobu, Akio, Saegusa, Jun, Kasagi, Shimpei, Fujita, Masaaki, Miyamoto, Yoshiaki, Matsuki, Fumichika, Kumagai, Shunichi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3218887/
https://ncbi.nlm.nih.gov/pubmed/21592365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3339
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