Sequencing of short cfDNA fragments in NIPT improves fetal fraction with higher maternal BMI and early gestational age

Low fetal DNA fraction (< 4%) samples obtained during noninvasive prenatal testing (NIPT) are responsible for 0.5%-3% of “no calls”. Maternal characteristics such as body mass index (BMI) and gestational age (GA) are the main factors that influence fetal fraction. Here, we improved fetal fraction...

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Publicado en:Am J Transl Res
Autores principales: Qiao, Longwei, Zhang, Qin, Liang, Yuting, Gao, Ang, Ding, Yang, Zhao, Nannan, Zhang, Wei, Li, Hong, Lu, Yaojuan, Wang, Ting
Formato: Artigo
Lenguaje:Inglês
Publicado: e-Century Publishing Corporation 2019
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6684886/
https://ncbi.nlm.nih.gov/pubmed/31396348
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