Sequencing of short cfDNA fragments in NIPT improves fetal fraction with higher maternal BMI and early gestational age

Low fetal DNA fraction (< 4%) samples obtained during noninvasive prenatal testing (NIPT) are responsible for 0.5%-3% of “no calls”. Maternal characteristics such as body mass index (BMI) and gestational age (GA) are the main factors that influence fetal fraction. Here, we improved fetal fraction...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Am J Transl Res
Main Authors: Qiao, Longwei, Zhang, Qin, Liang, Yuting, Gao, Ang, Ding, Yang, Zhao, Nannan, Zhang, Wei, Li, Hong, Lu, Yaojuan, Wang, Ting
Format: Artigo
Jezik:Inglês
Izdano: e-Century Publishing Corporation 2019
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6684886/
https://ncbi.nlm.nih.gov/pubmed/31396348
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