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Sequencing of short cfDNA fragments in NIPT improves fetal fraction with higher maternal BMI and early gestational age
Low fetal DNA fraction (< 4%) samples obtained during noninvasive prenatal testing (NIPT) are responsible for 0.5%-3% of “no calls”. Maternal characteristics such as body mass index (BMI) and gestational age (GA) are the main factors that influence fetal fraction. Here, we improved fetal fraction...
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| Vydáno v: | Am J Transl Res |
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| Hlavní autoři: | , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
e-Century Publishing Corporation
2019
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6684886/ https://ncbi.nlm.nih.gov/pubmed/31396348 |
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