Editing the immunopeptidome of melanoma cells using a potent inhibitor of endoplasmic reticulum aminopeptidase 1 (ERAP1)

The efficacy of cancer immunotherapy, including treatment with immune-checkpoint inhibitors, often is limited by ineffective presentation of antigenic peptides that elicit T-cell-mediated anti-tumor cytotoxic responses. Manipulation of antigen presentation pathways is an emerging approach for enhanc...

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Publicat a:Cancer Immunol Immunother
Autors principals: Koumantou, Despoina, Barnea, Eilon, Martin-Esteban, Adrian, Maben, Zachary, Papakyriakou, Athanasios, Mpakali, Anastasia, Kokkala, Paraskevi, Pratsinis, Harris, Georgiadis, Dimitris, Stern, Lawrence J., Admon, Arie, Stratikos, Efstratios
Format: Artigo
Idioma:Inglês
Publicat: Springer Berlin Heidelberg 2019
Matèries:
Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6684451/
https://ncbi.nlm.nih.gov/pubmed/31222486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-019-02358-0
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