Deletion of Kir5.1 Impairs Renal Ability to Excrete Potassium during Increased Dietary Potassium Intake

BACKGROUND: The basolateral potassium channel in the distal convoluted tubule (DCT), comprising the inwardly rectifying potassium channel Kir4.1/Kir5.1 heterotetramer, plays a key role in mediating the effect of dietary potassium intake on the thiazide-sensitive NaCl cotransporter (NCC). The role of...

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Wu, Peng, Gao, Zhong-Xiuzi, Zhang, Dan-Dan, Su, Xiao-Tong, Wang, Wen-Hui, Lin, Dao-Hong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2019
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6683724/
https://ncbi.nlm.nih.gov/pubmed/31239388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2019010025
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