Kir4.1/Kir5.1 Activity Is Essential for Dietary Sodium Intake–Induced Modulation of Na-Cl Cotransporter

BACKGROUND: Dietary sodium intake regulates the thiazide-sensitive Na-Cl cotransporter (NCC) in the distal convoluted tubule (DCT). Whether the basolateral, inwardly rectifying potassium channel Kir4.1/Kir5.1 (a heterotetramer of Kir4.1/Kir5.1) in the DCT is essential for mediating the effect of die...

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Foilsithe in:J Am Soc Nephrol
Main Authors: Wu, Peng, Gao, Zhong-Xiuzi, Su, Xiao-Tong, Wang, Ming-Xiao, Wang, Wen-Hui, Lin, Dao-Hong
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society of Nephrology 2019
Ábhair:
Basic Research
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6362624/
https://ncbi.nlm.nih.gov/pubmed/30559144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2018080799
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