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AT2R-mediated regulation of Na-Cl cotransporter (NCC) and renal K excretion depends on the K channel, Kir4.1
Angiotensin II (AngII) type 2 receptor (AT2R) is expressed in the distal nephrons. The aim of the present study is to examine whether AT2R regulates Na-Cl cotransporter (NCC) and Kir4.1 of the distal convoluted tubule (DCT). AngII inhibited the basolateral 40 pS K channel (a Kir4.1/5.1 heterotetrame...
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| Publicado no: | Hypertension |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5843543/ https://ncbi.nlm.nih.gov/pubmed/29483225 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.117.10471 |
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