O-cyclic phytosphingosine-1-phosphate stimulates HIF1α-dependent glycolytic reprogramming to enhance the therapeutic potential of mesenchymal stem cells

O-cyclic phytosphingosine-1-phosphate (cP1P) is a novel chemically synthesized sphingosine metabolite derived from phytosphingosine-1-phosphate. Although structurally similar to sphingosine-1-phosphate (S1P), its biological properties in stem cells remain to be reported. We investigated the effect o...

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Pubblicato in:Cell Death Dis
Autori principali: Lee, Hyun Jik, Jung, Young Hyun, Choi, Gee Euhn, Kim, Jun Sung, Chae, Chang Woo, Lim, Jae Ryong, Kim, Seo Yihl, Lee, Joo Eun, Park, Min Chul, Yoon, Jee Hyeon, Choi, Myeong Jun, Kim, Kye-Seong, Han, Ho Jae
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6683124/
https://ncbi.nlm.nih.gov/pubmed/31383843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1823-7
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