O-cyclic phytosphingosine-1-phosphate stimulates HIF1α-dependent glycolytic reprogramming to enhance the therapeutic potential of mesenchymal stem cells

O-cyclic phytosphingosine-1-phosphate (cP1P) is a novel chemically synthesized sphingosine metabolite derived from phytosphingosine-1-phosphate. Although structurally similar to sphingosine-1-phosphate (S1P), its biological properties in stem cells remain to be reported. We investigated the effect o...

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Publié dans:Cell Death Dis
Auteurs principaux: Lee, Hyun Jik, Jung, Young Hyun, Choi, Gee Euhn, Kim, Jun Sung, Chae, Chang Woo, Lim, Jae Ryong, Kim, Seo Yihl, Lee, Joo Eun, Park, Min Chul, Yoon, Jee Hyeon, Choi, Myeong Jun, Kim, Kye-Seong, Han, Ho Jae
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2019
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6683124/
https://ncbi.nlm.nih.gov/pubmed/31383843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1823-7
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