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Blood autophagy defect causes accelerated non-hematopoietic organ aging

Autophagy has been well studied in regulating aging; however, the impact of autophagy in one organ on the aging of other organs has not been documented. In this study, we used a mouse model with deletion of an autophagy-essential gene Atg7 in hematopoietic system to evaluate the intrinsic role of he...

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Podrobná bibliografie
Vydáno v:Aging (Albany NY)
Hlavní autoři: Fang, Yixuan, Zhu, Lingjiang, An, Ni, Jiang, Gaoyue, Qian, Jiawei, Zhao, Ruijin, Yuan, Na, Zhang, Suping, Wang, Jianrong
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6682532/
https://ncbi.nlm.nih.gov/pubmed/31327762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102086
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