Loss of Atg7 causes chaotic nucleosome assembly of mouse bone marrow CD11b(+)Ly6G(-) myeloid cells

Atg7, a critical component of autophagy machinery, is essential for counteracting hematopoietic aging. However, the non-autophagic role of Atg7 on hematopoietic cells remains fundamentally unclear. In this study, we found that loss of Atg7, but not Atg5, another autophagy-essential gene, in the hema...

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Sparad:
Bibliografiska uppgifter
I publikationen:Aging (Albany NY)
Huvudupphovsmän: Fang, Yixuan, Gu, Yue, Li, Lei, Zhu, Lingjiang, Qian, Jiawei, Zhao, Chen, Xu, Li, Wei, Wen, Du, Yanhua, Yuan, Na, Zhang, Suping, Yuan, Ye, Xu, Youjia, Jiang, Cizhong, Wang, Jianrong
Materialtyp: Artigo
Språk:Inglês
Publicerad: Impact Journals 2020
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7803583/
https://ncbi.nlm.nih.gov/pubmed/33232280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.104176
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