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A real-time, click chemistry imaging approach reveals stimulus-specific subcellular locations of phospholipase D activity

The fidelity of signal transduction requires spatiotemporal control of the production of signaling agents. Phosphatidic acid (PA) is a pleiotropic lipid second messenger whose modes of action differ based on upstream stimulus, biosynthetic source, and site of production. How cells regulate the local...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Liang, Dongjun, Wu, Kane, Tei, Reika, Bumpus, Timothy W., Ye, Johnny, Baskin, Jeremy M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6681737/
https://ncbi.nlm.nih.gov/pubmed/31311871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1903949116
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