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Spatiotemporal control of phosphatidic acid signaling with optogenetic, engineered phospholipase Ds

Phosphatidic acid (PA) is both a central phospholipid biosynthetic intermediate and a multifunctional lipid second messenger produced at several discrete subcellular locations. Organelle-specific PA pools are believed to play distinct physiological roles, but tools with high spatiotemporal control a...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Tei, Reika, Baskin, Jeremy M.
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7054994/
https://ncbi.nlm.nih.gov/pubmed/31999306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201907013
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