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Spatiotemporal control of phosphatidic acid signaling with optogenetic, engineered phospholipase Ds
Phosphatidic acid (PA) is both a central phospholipid biosynthetic intermediate and a multifunctional lipid second messenger produced at several discrete subcellular locations. Organelle-specific PA pools are believed to play distinct physiological roles, but tools with high spatiotemporal control a...
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| Published in: | J Cell Biol |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Rockefeller University Press
2020
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7054994/ https://ncbi.nlm.nih.gov/pubmed/31999306 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201907013 |
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