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A Chemoenzymatic Strategy for Imaging Cellular Phosphatidic Acid Synthesis

Phosphatidic acid (PA) is a potent lipid secondary messenger whose synthesis is tightly regulated in both space and time. Established tools for detecting PA involve ex vivo analysis and do not provide information on the subcellular locations where this lipid is synthesized. Here we report a chemoenz...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Bumpus, Timothy W., Baskin, Jeremy M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5153663/
https://ncbi.nlm.nih.gov/pubmed/27633714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201607443
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