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The Impact of FcγRI Binding on Immuno-PET
Antibodies are promising vectors for PET imaging. However, the high uptake of radioimmunoconjugates in nontarget tissues such as the liver and spleen hampers their performance as radiotracers. This off-target uptake can lead to suboptimal tumor–to–background activity concentration ratios, decreasing...
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| Pubblicato in: | J Nucl Med |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Society of Nuclear Medicine
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6681692/ https://ncbi.nlm.nih.gov/pubmed/30733320 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.118.223636 |
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