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The Impact of FcγRI Binding on Immuno-PET

Antibodies are promising vectors for PET imaging. However, the high uptake of radioimmunoconjugates in nontarget tissues such as the liver and spleen hampers their performance as radiotracers. This off-target uptake can lead to suboptimal tumor–to–background activity concentration ratios, decreasing...

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Bibliografiska uppgifter
I publikationen:J Nucl Med
Huvudupphovsmän: Vivier, Delphine, Sharma, Sai Kiran, Adumeau, Pierre, Rodriguez, Cindy, Fung, Kimberly, Zeglis, Brian M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Society of Nuclear Medicine 2019
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6681692/
https://ncbi.nlm.nih.gov/pubmed/30733320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.118.223636
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