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A Site-Specifically Labeled Antibody-Drug Conjugate for Simultaneous Therapy and ImmunoPET

The conjugation of antibodies with cytotoxic drugs can alter their in vivo pharmacokinetics. As a result, the careful assessment of the in vivo behavior — and specifically the tumor-targeting properties — of antibody-drug conjugates represents a crucial step in their development. In order to facilit...

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Detalhes bibliográficos
Publicado no:Mol Pharm
Main Authors: Adumeau, Pierre, Vivier, Delphine, Sharma, Sai Kiran, Wang, Jessica, Zhang, Terry, Chen, Aimei, Agnew, Brian J., Zeglis, Brian M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6466629/
https://ncbi.nlm.nih.gov/pubmed/29356543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.7b00802
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