Synthesis and Comparative In Vivo Evaluation of Site-Specifically Labeled Radioimmunoconjugates for DLL3-Targeted ImmunoPET

[Image: see text] Delta-like ligand 3 (DLL3) is a therapeutic target for the treatment of small cell lung cancer, neuroendocrine prostate cancer, and isocitrate dehydrogenase mutant glioma. In the clinic, DLL3-targeted (89)Zr-immunoPET has the potential to aid in the assessment of disease burden and...

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Publicat a:Bioconjug Chem
Autors principals: Sharma, Sai Kiran, Adumeau, Pierre, Keinänen, Outi, Sisodiya, Vikram, Sarvaiya, Hetal, Tchelepi, Robert, Korsen, Joshua A, Pourat, Jacob, Edwards, Kimberly J., Ragupathi, Ashwin, Hamdy, Omar, Saunders, Laura R., Rudin, Charles M., Poirier, John T., Lewis, Jason S., Zeglis, Brian M.
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2021
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8295218/
https://ncbi.nlm.nih.gov/pubmed/33835770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.1c00121
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