Synthesis and Comparative In Vivo Evaluation of Site-Specifically Labeled Radioimmunoconjugates for DLL3-Targeted ImmunoPET

[Image: see text] Delta-like ligand 3 (DLL3) is a therapeutic target for the treatment of small cell lung cancer, neuroendocrine prostate cancer, and isocitrate dehydrogenase mutant glioma. In the clinic, DLL3-targeted (89)Zr-immunoPET has the potential to aid in the assessment of disease burden and...

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發表在:Bioconjug Chem
Main Authors: Sharma, Sai Kiran, Adumeau, Pierre, Keinänen, Outi, Sisodiya, Vikram, Sarvaiya, Hetal, Tchelepi, Robert, Korsen, Joshua A, Pourat, Jacob, Edwards, Kimberly J., Ragupathi, Ashwin, Hamdy, Omar, Saunders, Laura R., Rudin, Charles M., Poirier, John T., Lewis, Jason S., Zeglis, Brian M.
格式: Artigo
語言:Inglês
出版: American Chemical Society 2021
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC8295218/
https://ncbi.nlm.nih.gov/pubmed/33835770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.1c00121
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