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Structural and Biological Investigations for a Series of N-5 Substituted Pyrrolo[3,2-d]pyrimidines as Potential Anti-Cancer Therapeutics

Pyrrolo[3,2-d]pyrimidines have been studied for many years as potential lead compounds for the development of antiproliferative agents. Much of the focus has been on modifications to the pyrimidine ring, with enzymatic recognition often modulated by C2 and C4 substituents. In contrast, this work foc...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Cawrse, Brian M., Robinson, Nia’mani M., Lee, Nina C., Wilson, Gerald M., Seley-Radtke, Katherine L.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6680647/
https://ncbi.nlm.nih.gov/pubmed/31340431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24142656
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