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Ring‐Opening Regio‐, Diastereo‐, and Enantioselective 1,3‐Chlorochalcogenation of Cyclopropyl Carbaldehydes

meso‐Cyclopropyl carbaldehydes are treated in the presence of an organocatalyst with sulfenyl and selenyl chlorides to afford 1,3‐chlorochalcogenated products. The transformation is achieved by a merged iminium–enamine activation. The enantioselective desymmetrization reaction, leading to three adja...

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Publicado en:Chemistry
Main Authors: Wallbaum, Jan, Garve, Lennart K. B., Jones, Peter G., Werz, Daniel B.
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6680189/
https://ncbi.nlm.nih.gov/pubmed/27868248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201605265
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