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Modelling the MYC-driven normal-to-tumour switch in breast cancer

The potent MYC oncoprotein is deregulated in many human cancers, including breast carcinoma, and is associated with aggressive disease. To understand the mechanisms and vulnerabilities of MYC-driven breast cancer, we have generated an in vivo model that mimics human disease in response to MYC deregu...

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Podrobná bibliografie
Vydáno v:Dis Model Mech
Hlavní autoři: Lourenco, Corey, Kalkat, Manpreet, Houlahan, Kathleen E., De Melo, Jason, Longo, Joseph, Done, Susan J., Boutros, Paul C., Penn, Linda Z.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Company of Biologists Ltd 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6679384/
https://ncbi.nlm.nih.gov/pubmed/31350286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.038083
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