Identification of c-MYC SUMOylation by mass spectrometry.

The c-MYC transcription factor is a master regulator of many cellular processes and deregulation of this oncogene has been linked to more than 50% of all cancers. This deregulation can take many forms, including altered post-translational regulation. Here, using immunoprecipitation combined with mas...

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Main Authors: Manpreet Kalkat, Pak-Kei Chan, Amanda R Wasylishen, Tharan Srikumar, Sam S Kim, Romina Ponzielli, David P Bazett-Jones, Brian Raught, Linda Z Penn
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science (PLoS) 2014-01-01
Serija:PLoS ONE
Online dostop:http://europepmc.org/articles/PMC4270761?pdf=render
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