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Modelling the MYC-driven normal-to-tumour switch in breast cancer

The potent MYC oncoprotein is deregulated in many human cancers, including breast carcinoma, and is associated with aggressive disease. To understand the mechanisms and vulnerabilities of MYC-driven breast cancer, we have generated an in vivo model that mimics human disease in response to MYC deregu...

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Detalhes bibliográficos
Publicado no:Dis Model Mech
Main Authors: Lourenco, Corey, Kalkat, Manpreet, Houlahan, Kathleen E., De Melo, Jason, Longo, Joseph, Done, Susan J., Boutros, Paul C., Penn, Linda Z.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6679384/
https://ncbi.nlm.nih.gov/pubmed/31350286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.038083
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