Auraptene Mitigates Parkinson’s Disease-Like Behavior by Protecting Inhibition of Mitochondrial Respiration and Scavenging Reactive Oxygen Species

Current therapeutics for Parkinson’s disease (PD) are only effective in providing relief of symptoms such as rigidity, tremors and bradykinesia, and do not exert disease-modifying effects by directly modulating mitochondrial function. Here, we investigated auraptene (AUR) as a potent therapeutic rea...

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Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Jang, Yunseon, Choo, Hyosun, Lee, Min Joung, Han, Jeongsu, Kim, Soo Jeong, Ju, Xianshu, Cui, Jianchen, Lee, Yu Lim, Ryu, Min Jeong, Oh, Eung Seok, Choi, Song-Yi, Chung, Woosuk, Kweon, Gi Ryang, Heo, Jun Young
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6679046/
https://ncbi.nlm.nih.gov/pubmed/31336718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20143409
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