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Whole Genome Microarray Analysis of DUSP4-Deletion Reveals A Novel Role for MAP Kinase Phosphatase-2 (MKP-2) in Macrophage Gene Expression and Function

Background: Mitogen-activated protein kinase phosphatase-2 (MKP-2) is a type 1 nuclear dual specific phosphatase (DUSP-4). It plays an important role in macrophage inflammatory responses through the negative regulation of Mitogen activated protein kinase (MAPK) signalling. However, information on th...

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Bibliographische Detailangaben
Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Neamatallah, Thikryat, Jabbar, Shilan, Tate, Rothwelle, Schroeder, Juliane, Shweash, Muhannad, Alexander, James, Plevin, Robin
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6679025/
https://ncbi.nlm.nih.gov/pubmed/31336892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20143434
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